Chapter 6: Clinical Validation of Radiobiological (RB) Models

Present study conclude that Indian patients of head and neck cancers treated with radiotherapy have better tolerance for OAR (parotid gland and oral cavity) with respect to recommended dose constraint. The patients enrolled in the study is single institutional based and treated in government hospital. Mostly patients treated in our institute belonged to low socio-economic status and cannot afford good diet. Even though patient reported higher tolerance of associated toxicity which is contradictory with the patients of western and European countries those have better socio-economic status. This difference can be possible with multiple reasons such as error in reporting toxicity, physiology of Indian patients, inherent tolerance capacity and single institutional study.