Synthesis and Structural Study of Complex Ligands and Derivatives of Carbohydrate Oxazoline from Amino-Sugar

A metal complexes were developed in this study, utilizing ligands derivatives of carbohydrate 1, 3-oxazolidine from amino-sugar modified (L₁ and L₂). The elemental analyses suggested that the stoichiometry is (1:2). The IR data confirmed the binding between the metal ion and the ligands. The crystallinity of the complexes formed was confirmed by the X-ray diffraction. The non-electrolyte nature of metal complexes was confirmed by molar conductance studies. The thermal study suggested the presence of coordinated water molecules in the complexes based on L₂. The synthesized complexes and their corresponding ligands were tested for their antimicrobial activities against bacteria (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumonia). The complexes (Zn(L₂)₂ and Ni(L₂)₂ showed significant antibacterial activity compared to the corresponding ligands. The dosage with the radical 2,2-diphenyl-1-picrylhydrazyl at different concentrations for the complexes (Ni(L₁)₂ and Ni(L₂)₂ showed superior antioxidant activity than the corresponding ligands. The considerable results found proved that the ligands and their complexes are bioactive.