Antioxidant and Protective Effects of Bioactive Compounds Contained In the Hydro-ethanolic extract of Olive Pomace against Cellular Alterations Induced by Streptozotocin in Diabetic Rats

Authors

Benmeliani Fatiha
Pathophysiology and Biochemistry of Nutrition Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe Sciences, University of Tlemcen, Algeria
Guermouche Baya
Pathophysiology and Biochemistry of Nutrition Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe Sciences, University of Tlemcen, Algeria
Belyagoubi-Benhammou Nabila
Natural Products Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe Sciences, University of Tlemcen, Algeria
Habi salim
Pathophysiology and Biochemistry of Nutrition Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe Sciences, University of Tlemcen, Algeria
Medjdoub Houria
Laboratory Antifungal,Antibiotic,physico-chemical,Synthesis and Biological Activity, Departement of Biology,Faculty of Natural Sciences and Life, Sciences of the Earth and the Universe,University Abou Bekr Belkaid Tlemcen, Algeria
Merzouk Hafida
Pathophysiology and Biochemistry of Nutrition Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe Sciences, University of Tlemcen, Algeria

Synopsis

The phenol-rich olive pomace (OP) extract showed significant benefits in treated diabetic rats, improving body weight (BW)and blood sugar levels. It notably reduced transaminases and lipid levels while enhancing hepatic antioxidant status and lowering malondialdehyde (MDA) content. Histopathological analysis demonstrated a decrease in hepatic morphological changes control.

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Published
December 4, 2024