Optimization of Ultrasound-Assisted Extraction Conditions for Phenolic Content and Antioxidant activities of Quercus Ilex Using Response Surface Methodology

The valorization of medicinal plants has gained significant attention due to their therapeutic properties. In this study, the optimization of the extraction of secondary metabolites and antioxidant activity from medicinal plant Quercus Ilex using ultrasound technique and applying the Response Surface Methodology (RSM) based on a CCD Centered Composite Design were carried out. This approach demonstrated promising results in extracting bioactive compounds from medicinal plants and provide a sustainable and efficient means of producing pharmaceuticals while preserving natural resources.