Development of an Implantable Matrix from Biodegradable Polymer for Prolonged Release of Active Substance Physico-Chemical and Biopharmaceutical Characterization

Authors

Ayachi Nabila
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Nadji L
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
ykhlef ilham iméne
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Tlidjani nada yasmine
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Madaoui batoule
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Guenaoui Radia
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Belhadji Linda
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria
Hadjsadok Abdelkader
Research Laboratory in Functional Analysis of Chemical Processes Department of Process Engineering Faculty of Technology University of Blida 1, Algeria

Synopsis

The aim of this study is to create a hydrophilic matrix from a biopolymer: chitosan, so that it can be used as a biodegradable implant. The selection of this matrix is motivated by the possibility of using a simple technology to manufacture direct compression mini compresses, in order to obtain a prolonged release of the active ingredient, Diclofenac

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Published
December 4, 2024