COVID -19 Vaccination: Hindrance for Organ Transplantation

Authors

Shakti Sharma
Chandigarh College of Pharmacy
Sonali Singh
Chandigarh College of Pharmacy

Synopsis

Outcome and survival after solid organ transplantation improved significantly in the last 15 years, leading to a need for new and effective preventive measures to maintain general health. Immuno-suppressive regimens put these patients at higher risk of life threating infection. Vaccination can prevent disease and decrease the replication and dissemination of infectious micro-organism. Therefore, specific vaccines have been recommended including pneumococcal, influenza and hepatitis A and hepatitis B, in selected cases tetanus, diphtheria and haemophilus influenza type B are used. However, the efficacy, safety, and protocols of several vaccines in the patient population are poorly understood. Due to immune-suppression regimens, several questions arise. Firstly, what is the effect of immune-suppression on the efficacy of pre-transplant covid-19 vaccination? Secondly, if covid-19 vaccination can be given post-transplantation can efficacy of covid-19 vaccine hinder the post-transplant phase? Thirdly, what can be the duration between post transplantation phase and covid-19 vaccination?

 

LR
Published
February 1, 2023